Urea is an natural and organic substance that is probably more known for its role within a fertilizer made use of in agriculture. Urea takes on an important part in your bodies metabolism and is a vital method by which the body eliminates unnecessary nitrogen. It is manufactured within the liver from an ammonia compound via the breakdown of amino acids as being the major result of protein metabolism. It is comprised of two amine chemicals that are bound with each other by a carbonyl chemical group. Back in 1928 the chemist, Friedrich Wöhler proved for the first time that the organic compound may be crafted from inorganic chemical substances when he was able to construct urea from its inorganic components in the research laboratory. The manufactured version of urea is regularly used as a topical cream or external medicine employed to care for an array of skin problems. It’s become so essential because of this that urea is currently listed by the WHO on the List of Essential Medicines which it advocates that most nations be able to access. In skin which is dried out, many experts have shown that there is a considerable loss of urea in your skin, therefore hence the need to use the urea lotions. These kind of skin complaints include simple skin conditions like dried-out skin or the more severe skin disorders including psoriasis, eczema along with ichthyosis. These kinds of ointments are often times made use of by podiatric physicians following the removal of cracked skin surrounding the heels.
These urea lotions have different impacts on different skin complaints determined by their content level in the cream. At levels near 40% the urea can reduce the cellular matrix in the nail plate so can be used to take care of nail dystrophy disorders by dissolving an area of the toenail. This could be useful for disorders like tinea infections on the toe nails. At amounts under that, whilst still being above 20% the urea lotion is known as a keratolytic which means it can cause a breakdown of proteins in your skin, so the dry skin might slough off, especially with the damaged dried-out skin surrounding the heel of the foot. At concentrations of less than about 20% the urea cream acts as a humectant which suggests it can help your skin hold on to moisture and lower water loss and make the skin soft in addition to flexible. Urea comes with a extra benefit because it also has anti itching actions meaning that it may help with those dryer skin complaints that happen to be also itching. There are not really any adverse effects by using these urea products on the epidermis with the exception of an infrequent local aggravation that almost usually clears up when you cease using the urea product. In contrast to a great deal of other medicines, there aren’t any known interactions between urea and some other medicines that may be used. Urea shouldn’t be used if there is a recognized allergy to urea or any of the other substances that are utilized when making the cream. There are practically 100’s of various manufacturers of urea creams including the Walker’s Urea Foot Cream from Australia as well as Glycolix’s Glyco-Urea KP Therapy in the US. At all times steer clear of exposure to your eyes with the urea cream and rinse the hands right after making use of it.